Q500 Sonicator

Manufactured in the United States
based on 3 reviews

The Q500 is a powerful, 500 watt ultrasonic processor featuring programmable operation and a digital display of operating parameters. Suitable applications include nanoparticle dispersion, creating emulsions, cell lysis and homogenization.

Adjustable pulse On and Off times can be programmed from 1 second to 1 minute. Total programming has a maximum setting of 10 hours. A wide variety of probes and accessories are available to handle virtually any application.

  • Programmable operation - Set time and amplitude for hands free operation
  • Pulse mode - Prevent heat buildup in temperature sensitive samples
  • Digital amplitude / intensity control - Output intensity can be set from 20-100%
  • Elapsed time indicator - Displays duration of sonication
  • Display of wattage and joules - Real-time energy monitoring
  • Overload protection - Prevents damage to circuitry if a fault occurs
  • RoHS compliant - Uses lead free components

The Q500 Sonicator can be purchased with or without a standard 1/2” diameter probe with replaceable tip.  A variety of probe / horn options are available; please click the button below for horns and other accessories or click here for standard probes.

Please note: There is a 2 - 3 week lead time on all Sonicator units.  Expedited processing, which decreases the lead time to 5 days, is offered for an additional $150.

Key Attributes
Homogenizer Type Ultrasonic
Sample Throughput 1 sample
Sample Volume (min) 200 µl
Sample Volume (max) 1 l
Usage / Placement Benchtop
Cooling No
Warranty 2 years
Noise Level
Weight 15 lb
Width 8"
Depth 15.25"
Height 8.5"
Manufacturer Specifications
  • Power Rating: 500 watts
  • Frequency: 20 kHz
  • Programmable Timer: 10 hours
  • Adjustable Pulse On/Off: 1 second to 1 minute
  • Dimensions: 8″ W x 15.25″ L x 8.5″ H
  • Voltage: 110V, 50/60Hz

Does the Q500 have any mechanism such as RS232 that would allow it to be controlled by a computer?

While the Q500 does not have RS232, it does have a 9-pin D-sub connector to a programmable logic controller. The connector has the following configuration:

Sonicator 9-pin D-sub connector layout


I have a high-temperature application. What is the maximum temperature that I can operate the probe in?

The probe itself can withstand temperatures as high as 140°F / 60°C. Higher temperature applications can be accommodated, but they require a custom probe. Please contact us with the details of your application to see if a special probe can be designed for it.


What are the probes made of?

Titanium alloy Ti-6Al-4V.


How viscous of a substance can a Sonicator homogenize?

A good rule of thumb is if you can’t pour it then you can’t sonicate it. Substances with approximately the viscosity of honey (around 4000 cps) are the most viscous substances that a Sonicator can effectively process.


Is the Q500 UL listed or CSA approved?

Not explicitly, but all Sonicators are cTUVus certified. This certification combines the common UL and CSA standards for electronic equipment and is accepted as equivalent for most regulatory purposes.

Looking for Q500 Sonicator Accessories?

Click here


SKU#: QS:Q500A-110

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Customer reviews

based on 3 reviews