Ultrasonic Homogenizers (Sonicators)

Ultrasonic homogenizers, commonly referred to as "sonicators," disrupt tissues and cells through cavitation and ultrasonic waves.  Basically, an ultrasonic homogenizer has a tip which very rapidly vibrates, causing bubbles in the surrounding solution to rapidly form and collapse.  This creates shear and shock waves which tear apart cells and particles.

Ultrasonics / sonicators are great for breaking apart cells and subcellular structures in suspension.  They are not good for homogenizing intact tissue.  Ultrasonic homogenizers can also shear DNA, which could be a good thing or a bad thing depending on your application.  Other applications include creating emulsions, dispersing nanoparticles, and reducing the size of particles in suspension.  Sonicators generate a significant amount of heat so they may not work well with temperature-sensitive samples.  Acoustic enclosures are highly recommended; after all, you're homogenizing using high-powered sound waves.  You can learn more about ultrasonic homogenization in the application center.

Uncertain if an ultrasonic is the right homogenizer for your application?  We can help!  Ask us anything.


  • On sale
    A powerful, 500 watt ultrasonic processor with programmable operation and a digital display.
    $3,750 USD   from   $3,375 USD
    based on 3 reviews
  • On sale
    A compact and low-cost ultrasonic homogenizer for low-volume applications.
    $1,840 USD   from   $1,656 USD
    based on 1 review
  • On sale
    A digital, programmable ultrasonic homogenizer suitable for small volumes.
    $2,885 USD   from   $2,597 USD
    based on 3 reviews
  • On sale
    A ready-to-use, analog ultrasonic homogenizer system for high or low power applications, or anything in between.
    $3,555 USD   from   $2,950 USD
    based on 1 review
  • On sale
    A powerful, flexible, 700-watt sonicator with a touchscreen display and full amplitude control from 1-100%.
    $4,860 USD   from   $4,374 USD
  • On sale
    A digital, ready-to-use ultrasonic homogenizer system for low-power applications with option for handheld operation.
    $3,295 USD   from   $2,710 USD
    based on 1 review
  • On sale
    A very high-powered, 1375 watt ultrasonic homogenizer for industrial-scale applications up to 40L or 5L/min.
    $8,790 USD   from   $7,911 USD
    based on 2 reviews
  • On sale
    A digital, ready-to-use ultrasonic homogenizer system for mid to low power applications.
    $3,850 USD   from   $3,425 USD
    based on 1 review
  • No sale
    Automated homogenization system with rotor-stator and ultrasonic capabilities. You get what you pay for.
      from   $18,469 USD
  • On sale
    A ready-to-use, analog ultrasonic homogenizer system for mid to low power applications.
    $3,162 USD   $2,535 USD
  • No sale
    All the features necessary to create a total system for 300 watts of ultrasonic disruption
      $2,786 USD
  • No sale
    Delivers 300 watts of ultrasonic disruption and includes an integrated Sound Abating Chamber
      $3,181 USD
  • No sale
    All the features necessary to create a total system for 150 watts of ultrasonic disruption
      $2,186 USD
  • No sale
    Precision control microprocessor, graphical user interface, and an integrated Sound Abating Chamber
      $3,781 USD