The Application Center exists to help you achieve better results and make better purchasing decisions by providing you with a plethora of information on homogenizers and homogenization. Here, you'll find detailed information on homogenization technologies, applications, and specific protocols for certain types of samples and homogenizers.
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Browse all protocols in the protocol directory, or use the search bar below to search for a protocol for your specific application.
Rotor-Stator
Rotor-stator homogenizers use rotary mechanical force to homogenize samples. A very rapidly spinning rotor is tightly fitted within a stationary outer case (the stator). This motion causes a vigorous mixing which draws liquid or particles into the space between the rotor and stator, where ultra-high shear forces homogenize the material. More info.
Ultrasonic
Ultrasonic homogenizers generate intense sonic shock waves in liquid media. A rapidly moving tip causes the inertial cavitation: the rapid formation and collapse of vapor cavities. This releases a large amount of energy, which breaks apart particles and produces a thorough mixing, homogenizing the sample. More info.
Bead Mill
In a bead mill homogenizer, the sample is placed in a tube with beads and the tubes are vigorously shaken. The movement of the beads and the collisions caused by the rapidly moving beads homogenize the sample. More info.
High-Pressure
This method involves forcing a mixture under extremely high-pressure through a narrow channel or opening. When passing through the channel, the particles experience a very high pressure drop, causing high amounts of shear and reducing particle sizes. More info.
Paddle Blender
Paddle blenders, often called stomachers, are not typical homogenizers in they do not create a homogeneous mixture from the sample. Instead, they squeeze the sample in order to extract things from it, usually bacteria or live cells. More info.
Mortar & Pestle
These consist of a hard, blunt object (the pestle) which is pressed against a sample container (the mortar). The sample is squeezed between the mortar and pestle to grind and homogenize it. Mortar & Pestle homogenizers may be manual or motorized. They are generally lower-throughput and used for relatively small samples which are processed one at a time. Used in life science applications, these are often known as tissue grinders. More info.
