Ultrasonic Homogenizers (Sonicators)

Ultrasonic homogenizers, commonly referred to as "sonicators," disrupt tissues and cells through cavitation and ultrasonic waves.  Basically, an ultrasonic homogenizer has a tip which very rapidly vibrates, causing bubbles in the surrounding solution to rapidly form and collapse.  This creates shear and shock waves which tear apart cells and particles.

Ultrasonics / sonicators are great for breaking apart cells and subcellular structures in suspension.  They are not good for homogenizing intact tissue.  Ultrasonic homogenizers can also shear DNA, which could be a good thing or a bad thing depending on your application.  Other applications include creating emulsions, dispersing nanoparticles, and reducing the size of particles in suspension.  Sonicators generate a significant amount of heat so they may not work well with temperature-sensitive samples.  Acoustic enclosures are highly recommended; after all, you're homogenizing using high-powered sound waves.  You can learn more about ultrasonic homogenization in the application center.

Uncertain if an ultrasonic is the right homogenizer for your application?  We can help!  Ask us anything.

  • On sale
    A compact and low-cost ultrasonic homogenizer for low-volume applications.
    based on 2 reviews
    $1,850 USD   from   $1,665 USD
  • On sale
    A powerful, 500 watt ultrasonic processor with programmable operation and a digital display.
    based on 6 reviews
    $3,780 USD   from   $3,402 USD
  • On sale
    A digital, programmable ultrasonic homogenizer suitable for small volumes.
    based on 3 reviews
    $2,895 USD   from   $2,606 USD
  • On sale
    A powerful, flexible, 700-watt sonicator with a touchscreen display and full amplitude control from 1-100%.
    $4,860 USD   from   $4,374 USD
  • On sale
    Industrial-scale sample volumes up to 30L, 2000 watt ultrasonic homogenizer
    $11,000 USD   from   $9,900 USD