Q125 Sonicator

Category Ultrasonic Homogenizer
Manufacturer Qsonica
Country of manufacture the United States
Average customer rating based on 5 reviews

The Q125 is a digital, programmable ultrasonic processor. Features include pulse mode and a digital display of both wattage and joules.

This 125 watt unit is effective for standard cell disruption, DNA/RNA shearing, homogenization and many other applications. The Q125 is ideal for small samples and for users who will not need to scale up to larger volumes in the future. Adjustable pulse On and Off times can be programmed from 1 second to 1 minute. Total programming has a maximum setting of 10 hours.

  • Programmable operationSet time and amplitude for hands free operation
  • Pulse mode - Prevent heat buildup in temperature sensitive samples
  • Digital amplitude / intensity control - Output intensity can be set from 20-100%
  • Elapsed time indicator - Displays duration of sonication
  • Display of wattage and joules - Real-time energy monitoring
  • Overload protection - Prevents damage to circuitry if a fault occurs
  • RoHS compliant - Uses lead free components
  • Compact design - Takes up less space than competitive units

The Q125 Sonicator can be purchased with or without a standard 1/8” diameter probe.  A variety of probe / horn options are available; please click the button below for all accessories.

Please note: There is a 2 - 3 week lead time on all Sonicator units.  Expedited processing, which decreases the lead time to 5 days, is offered for an additional $150. A stand is not included with purchase.

Key Attributes
Homogenizer Type Ultrasonic
Sample Throughput 1 sample
Sample Volume (min) 200 µl
Sample Volume (max) 50 ml
Usage / Placement Benchtop
Cooling No
Warranty 2 years
Noise Level
Weight 7 lb
Width 8"
Depth 13.75"
Height 5.75"
Manufacturer Specifications
  • Power Rating: 125 watts
  • Frequency: 20 kHz
  • Programmable Timer: 10 hours
  • Adjustable Pulse On/Off: 1 second to 1 minute
  • Dimensions" 8″ W x 13.75″ L x 5.75″ H
  • Voltage" 110V, 50/60Hz

Does the Q125 have any mechanism such as RS232 that would allow it to be controlled by a computer?

While the Q125 does not have RS232, it does have a 9-pin D-sub connector to a programmable logic controller. The connector has the following configuration:

Sonicator 9-pin D-sub connector layout


I have a high-temperature application. What is the maximum temperature that I can operate the probe in?

The probe itself can withstand temperatures as high as 140°F / 60°C. Higher temperature applications can be accommodated, but they require a custom probe. Please contact us with the details of your application to see if a special probe can be designed for it.


What are the probes made of?

Titanium alloy Ti-6Al-4V.


How viscous of a substance can a Sonicator homogenize?

A good rule of thumb is if you can’t pour it then you can’t sonicate it. Substances with approximately the viscosity of honey (around 4000 cps) are the most viscous substances that a Sonicator can effectively process.


Is the Q125 UL listed or CSA approved?

Not explicitly, but all Sonicators are cTUVus certified. This certification combines the common UL and CSA standards for electronic equipment and is accepted as equivalent for most regulatory purposes.


How frequently does the ultrasonic horn (probe) need to be replaced?

Unfortunately that doesn't have a set answer. There are too many variables that effect the life of a horn and Qsonica has never done a study on the life span of a horn. Under light use and an application that is easy on the horn, an ultrasonic horn might last years. With continuous use and an unfavorable application, it might only last days.

The life span of a horn is dependent on multiple factors, including but not limited to:

  • The presence of solids. Particulate will wear the horn. The larger, harder, and more concentrated the particulate, the faster the wear.
  • Acidic solutions will wear the horn faster than neutral or basic solutions.
  • Using the probe at higher amplitude will wear the horn faster.
  • The size of the probe. Smaller diameter horns wear faster than large ones, as they operate at higher amplitudes and have less titanium available to wear.

Ultimately, you will need to empirically determine how long your horn will last in your application. You'll know it needs replacing when your processing starts to become less efficient.


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    Customer reviews

    based on 5 reviews

    Q125 Sonicator Accessories