Genizer Online Liposome Extruders

Category Homogenizer Accessories
Manufacturer Genizer

Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of pharmaceutical liposomes for anti-cancer drugs. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Online Liposome Extruders are designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Online Liposome Extruder offers virtually no dead volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.


  • No dead volume
  • Online extruder can control the temperature of extrusion
Catalog No. GOE-25mL GOE-200mL GOE-1000mL GOE-8L GOE-20L
Sample Size 25mL 200mL 1000mL 8000mL 20000mL
Cooling Jacketed Jacketed Jacketed Jacketed Jacketed
Dimensions 10cm×10cm×8cm 13cm×13cm×9cm 18cm×18cm×10cm 30cm×25cm×25cm 45cm×40cm×30cm
Weight 1kg 2kg 5kg 25kg 90kg
Min. Sample Size 5mL 10mL 100mL 500mL 1000mL
Application Liposome formulation up to production scale; Sterile filtration
Max. Pressure 1,200 psi-3,500 psi
Temp. Limit 80ºC (176ºF)
Power Type High pressure pump or high pressure homogenizer
Nano-membrane Track-etched membrane
Cleaning Flush to clean/CIP/SIP
Sterilization Whole unit autoclavable
Standard Features
Parts 1) Liposome Online Extruder
2) 10 pieces of 100nm membrane
Filter Support Jacketed filter support with pagoda inlet and outlet 
Inlet Type 3/8" high pressure coupling
Outlet Type 3/8" high pressure coupling
Handle Handle for GOE-800mL, GOE-3000mL and GOE-10000mL
Nano Membrane 100nm track-etched polycarbonate membrane
Compatibility Some parts are compatible with Lipex in Northern Lipids
Product Material 316L stainless steel, viton
Material Standard Sanitary grade; compliant with FDA and GMP sanitary standards
Warranty 1 year against any manufacturing defects
Option Features
Detector 10,000psi sanitary pressure gauge with adaptor, pressure transducer, temperature transducer
Power Sanitary high pressure piston pump/hand pump
Inlet Type Tri-clamp or luer
Outlet Type Tri-clamp or luer
Nano membrane 30nm, 50nm, 80nm, 100nm, 200nm, 400nm, 800nm, 1000nm, 2μm, 5μm, 10μm, 20μm, 30μm track-etched membrane (25mm, 47mm, 90mm, 150mm, 293mm), 0.45μm/0.22μm for biological or sterile filtration
Multi Extruder Parallel or series connection of multi-extruder

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