Genizer Jacketed Liposome Extruders

Category Homogenizer Accessories
Manufacturer Genizer

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.


  • No dead volume
  • The Jacketed Extruder can control the temperature of the extrusion
Catalog No. GJE-10mL GJE-100mL GJE-800mL GJE-3000mL
Sample Size 10mL 100mL 800mL 3,000mL
Cooling Jacketed Jacketed Jacketed Jacketed
Dimensions 23cm×13cm×25cm 23cm×20cm×32cm 25cm×25cm×37cm 30cm×25cm×55cm
Weight 4kg 7kg 20kg 45kg
Min. Sample Size 5mL 10mL 120mL 800mL
Application Liposome formulation up to production scale
Max. Pressure 80 psi-500 psi
Max. Temp. 80ºC (176ºF)
Power Type Compressed gas
Nano-membrane Track-etched membrane
Cleaning Flush to clean/CIP/SIP
Sterilization Whole unit autoclavable
Standard Features
Parts 1) Liposome Jacketed Extruder 2) 10 pieces of 100nm membrane
Feed Reservoir Temperature-controled jacketed cylinder
Inlet Type 1/4" high pressure coupling
Outlet Type 1/4" high pressure coupling
Nitrogen Tubing G5/8" - 14 TPI BSP inlet nitrogen high pressure soft tubing; adaptor with 3/8-inch male NPT and 1/4-inch female flare outlet
Nano Membrane 100nm track-etched polycarbonate membrane
Compatibility Some parts are compatible with Lipex in Northern Lipids
Product Material 316L stainless steel, NBR  or FKM
Material Standard Sanitary grade; compliant with FDA and GMP sanitary standards
Warranty 1 year against any manufacturing defects
Option Features
Detector Pressure gauge, pressure transducer, temperature transducer
Inlet Type Tri-clamp or luer
Outlet Type Tri-clamp or luer
Nano Membrane 30, 50, 80, 130, 200, 400, 800nm, 1300nm, 2μm, 5μm, 10μm, 20μm, 30μm track-etched membrane (25mm, 47mm, 90mm, 160mm, 293mm)
Multi Extruder Parallel or series connection of multi-extruder

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