| Sample Size | SKU | Price |
|---|---|---|
| 10mL | GNZ:GJE-10mL |
$3,500
|
| 100mL | GNZ:GJE-100mL |
$5,000
|
| 800mL | GNZ:GJE-800mL |
$8,500
|
| 3000mL | GNZ:GJE-3000mL |
$15,000
|
The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.
Features:
| Catalog No. | GJE-10mL | GJE-100mL | GJE-800mL | GJE-3000mL |
| Sample Size | 10mL | 100mL | 800mL | 3,000mL |
| Cooling | Jacketed | Jacketed | Jacketed | Jacketed |
| Dimensions | 23cm×13cm×25cm | 23cm×20cm×32cm | 25cm×25cm×37cm | 30cm×25cm×55cm |
| Weight | 4kg | 7kg | 20kg | 45kg |
| Min. Sample Size | 5mL | 10mL | 120mL | 800mL |
| Application | Liposome formulation up to production scale | |||
| Max. Pressure | 80 psi-500 psi | |||
| Max. Temp. | 80ºC (176ºF) | |||
| Power Type | Compressed gas | |||
| Nano-membrane | Track-etched membrane | |||
| Cleaning | Flush to clean/CIP/SIP | |||
| Sterilization | Whole unit autoclavable | |||
| Standard Features | ||||
| Parts | 1) Liposome Jacketed Extruder 2) 10 pieces of 100nm membrane | |||
| Feed Reservoir | Temperature-controled jacketed cylinder | |||
| Inlet Type | 1/4" high pressure coupling | |||
| Outlet Type | 1/4" high pressure coupling | |||
| Nitrogen Tubing | G5/8" - 14 TPI BSP inlet nitrogen high pressure soft tubing; adaptor with 3/8-inch male NPT and 1/4-inch female flare outlet | |||
| Nano Membrane | 100nm track-etched polycarbonate membrane | |||
| Compatibility | Some parts are compatible with Lipex in Northern Lipids | |||
| Product Material | 316L stainless steel, NBR or FKM | |||
| Material Standard | Sanitary grade; compliant with FDA and GMP sanitary standards | |||
| Warranty | 1 year against any manufacturing defects | |||
| Option Features | ||||
| Detector | Pressure gauge, pressure transducer, temperature transducer | |||
| Inlet Type | Tri-clamp or luer | |||
| Outlet Type | Tri-clamp or luer | |||
| Nano Membrane | 30, 50, 80, 130, 200, 400, 800nm, 1300nm, 2μm, 5μm, 10μm, 20μm, 30μm track-etched membrane (25mm, 47mm, 90mm, 160mm, 293mm) | |||
| Multi Extruder | Parallel or series connection of multi-extruder | |||
