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Drug Analysis in Hair

Instrument: Precellys® 24 Dual

Sample:  Hair segments

Protocol:

  • Precellys kits: MK28 (metal beads)
  • Sample : 1cm hair segments
  • Buffer : empty
  • Precellys®24 parameters:
  • Run the Precellys at 6500 rpm, 2x50 sec., 15 sec. break

Results:

Analysis of an authentic hair sample by HPLC-MS/MS with the following steps :
1. Decontamination (Dichloromethane)
2. Grinding (Precellys®24)
3. Incubation (Methanol)
4. Centrifugation
5. Evaporation
6. Filtration
7. Analysis by HPLC-MS/MSThe Precellys24-Dual significantly decreases the time spent on sample preparation, increases the nutrient yield, and gives highly reproducible results.

Precellys®24 is successfully evaluated on hair grinding, which is considered a difficult and challenging sample. Results of toxicology tests in crime labs are now faster.